High-Throughput Lead Optimization in Drug Discovery (Critical Reviews in Combinatorial Chemistry) by Tushar Kshirsagar
English | 8 Apr. 2008 | ISBN: 0849372682 | 256 Pages | PDF | 10 MB
The end of the previous millennium saw an explosion in the application of parallel synthesis techniques for making compounds for high-throughput screening. Over time, it became clear that more thought in the design phase of library development is necessary to generate high quality hits.