Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics by William A. Craig M.D., Alexander A. Vinks
November 24, 2013 | ISBN: 0387756124 | Pages: 466 | PDF | 8 MB
Over the past decade, significant progress has been made in the theory and applications of pharmacodynamics of antimicrobial agents. On the basis of pharmacokinetic-pharmacodynamic modeling concepts it has become possible to describe and predict the time course of antimicrobial effects under normal and pathophysiological conditions. The study of pharmacokinetic-pharmacodynamic relationships can be of considerable value in understanding drug action, defining optimal dosing regimens, and in making predictions under new or changing pre-clinical and clinical circumstances.