Dr. Jimmy Kildare and Nurse Mary Lamont are all sent to get married and her brother Doug Lamont has come to New York. When Jimmy meets him he notices strange behavior on his part such as sudden inattention or acting as if he was hearing sounds that are non-existent. The doctor starts to diagnose him and comes to the conclusion that he probably has epilepsy, a hereditary disease that could conceivably affect Mary as well, even though she has never shown any symptoms. Dr. Kildare is worried about this part of medicine and how you tell someone that they have a disease that they can do nothing about. It's left to Dr. Leonard Gillespie to come up with a solution and ensure that Jimmy and Mary can still get married.
It is a week before Dr. Kildare's wedding to pretty Nurse Mary Lamont. The hospital is a-buzz with preparation for the big day. And good old Dr. Gillespie, despite fatigue, has agreed to help a prominent orchestra conductor regain his hearing. But soon tragedy strikes . . . will the hospital every be the same?
Kildare saves the life of an ice skater who was in an auto accident. But even though her broken leg has knit, she can't walk, and she tries to sue Kildare for malpractice, and Kildare's entire career and reputation now rests on making a proper diagnosis in the courtroom.
Dr. James Kildare has just completed his internship at Blair General Hospital and is assigned to work with his mentor, Dr. Leonard Gillespie. But fearing for the health of his father, Dr. Stephen Kildare, he returns to his parents home in Parkersville to help him with his excessive workload servicing a wide area ever since other doctors moved elsewhere. Noting that three doctors at Blair General are doing menial jobs because they can't start practice, Kildare conceives the idea of building a clinic in Parkersville to be serviced by the three doctors and financed by the townsfolk paying ten cents a week to subscribe to the service. But influential men in Parkersville provide serious opposition to the plan.
Dr. Jimmy Kildare is back at work at Blair General hospital, though several people admit that he is not himself since suffering his loss. He's taken a liking to a young intern, Don Winthrop, and tries to help him out when he transports an accident victim, socialite Cynthia "Cookie" Charles, to Blair General from outside the hospital's agreed territory. When the other hospital complains, Winthrop is fired. Soon after, his girlfriend, Nurse Anabelle Kirke, is also let go when she too misapplies hospital policy. Kildare pleads their case with the hospital Board but with little luck. He then gets the well-connected Cookie, who has a thing for him, to help to sort it out
Dr. Gillespie's cancer has gotten worse, and to force him to take a rest instead of pursuing a sulfa-drug/pneumonia study, Kildare refuses to assist Gillespie, and instead accepts a case of hysterical blindness. She's also the daughter of a millionaire who could help the hospital.
Young Dr. Kildare is still being trained at General Hospital by old, crusty Dr. Gillespie. This time, he tries to rehabilitate Gregory Lane, a brain surgeon depressed over losing too many patients (and incidentally Kildare's romantic rival for nurse Mary Lamont). Lane's losing streak takes a new turn when one of his patients survives…but seems to be insane. Or is the man's strange obsession with Friday the clue to a mystery? To find out, Kildare must take a terrible risk.
Fresh out of medical school, young Dr. James Kildare decides to leave his father's country practice and take up a position at a large New York hospital. There he meets the famous Dr. Leonard Gillespie who becomes his mentor. Kildare finds himself in serious trouble when he saves a suicidal woman who turns out to be an heiress with a powerful family.
Dr. Gillespie tries to teach Jimmy Kildare a lesson by tossing him into a street clinic. Only Kildare gets called to take a bullet out of a suspected murderer, and when the cops collar him for it, he has to try and prove his patient's innocence, especially for his sister Rosalie's sake.